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Vascular Medicine, Vol. 7, No. 2, 135-140 (2002)
DOI: 10.1191/1358863x02vm417ra

Biointerventional cardiology: the future interface of interventional cardiovascular medicine and bioengineering

Craig A Thompson

Cardiovascular Division and Cardiovascular Tissue Engineering Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA, cathompson{at}partners.org

Stephen N Oesterle

Cardiovascular Division and Cardiovascular Tissue Engineering Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Major advances in cardiovascular intervention for chronic disease are underway. These innovations lie at the interface of minimally invasive catheter-based technologies and biologic approaches for the management of complex cardiovasculardiseases. This review highlights key areas where such ‘biointerventional’ cardiovascular therapies are envisioned to occur: cardiac cell transplantation, myocardial gene therapy, genetic and photodynamic endovascular interventions, and vascular tissue engineering.

Key Words: bioengineering • cardiomyopathy • cardiomyoplasty • congestive heart failure • gene • percutaneous • tissue engineering


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