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Vascular Medicine
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Hemochromatosis associated with endothelial dysfunction: evidence for the role of iron stores in early atherogenesis

John Lekakis

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Christos Papamichael

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Kimon Stamatelopoulos

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Adriana Cimponeriu

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Anastasios Voutsas

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Konstantinos Vemmos

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Myron Mavrikakis

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Stamatios Stamatelopoulos

Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Athens, Greece

Impaired endothelium-dependent, flow-mediated dilatation of the brachial artery was observed in a 50-year-old premenopausal female non-smoker with idiopathic hemochromatosis. Endothelial dysfunction observed in this patient supports a relationship between body iron stores and early atherosclerotic process.

Key Words: endothelial function • hemochromatosis • iron stores

Vascular Medicine, Vol. 4, No. 3, 147-148 (1999)
DOI: 10.1177/1358836X9900400305
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